Cincinnati, OH – A 35-year-old man, identified as John Joshua Isome, has died after being shot late Tuesday night in Over-the-Rhine, according to Cincinnati Police. The shooting occurred in the 2000 block of Mohawk Place at approximately 11 p.m. on August 5, 2025.
Isome was shot in the head and chest, and despite efforts to provide assistance, he was pronounced dead at the scene. Initial reports incorrectly identified him as a 50-year-old man, but police later confirmed his correct age.
Details of the Shooting
According to law enforcement officials, John Joshua Isome was shot inside a vehicle. Police believe that Isome was picked up by the suspect before being shot in the vehicle where he was ultimately found. The vehicle was located in the area where he was discovered, but the suspect remains at large. The Cincinnati Police Department (CPD) has not released any information regarding the suspect’s identity or a possible motive for the shooting.
A firearm was discovered inside the vehicle at the scene, but it remains unclear if it was the weapon used in the shooting. Investigators are looking into the circumstances surrounding the discovery of the firearm and whether it played a role in the tragic incident.
Investigation and Search for Suspect
The Cincinnati Police Department has launched an active investigation into the shooting, and detectives are working to gather additional information about the incident. City surveillance cameras and business cameras in the area are being reviewed as part of the investigation to locate potential footage of the suspect or the shooting itself. Police are also speaking with witnesses and checking for any further clues that could help identify the person responsible.
At this time, no suspect information has been released to the public, and law enforcement officials are urging anyone who may have seen or heard something related to the shooting to come forward with information.
Public Appeal for Information
Cincinnati Police are asking residents of the Over-the-Rhine neighborhood, as well as anyone who may have been in the area, to contact law enforcement if they have any information that could assist with the investigation. Officers are particularly interested in any surveillance footage, witness statements, or any other details that might help piece together the events leading up to Isome’s death.
“Any information, no matter how small, could be crucial in bringing justice to Mr. Isome and his family,” said a spokesperson for the Cincinnati Police Department. “We urge the public to come forward and help us solve this case.”
Community Concerns and Impact
The shooting has left the Over-the-Rhine community in shock. Known for its vibrant culture and tight-knit atmosphere, the neighborhood is now grappling with the tragic loss of life in such a violent manner. Local residents have expressed concern over the safety of their community and are hoping that law enforcement will quickly identify the person responsible.
Neighbors who knew John Joshua Isome described him as a quiet and private individual who didn’t deserve to meet such a tragic end. His death has raised concerns about rising violence in the area, prompting calls for more community safety efforts and law enforcement presence.
Ongoing Investigation and Updates
The investigation into the shooting is still ongoing, and Cincinnati Police continue to search for the suspect responsible for this crime. As of now, no charges have been filed, and no suspects have been named. Investigators are continuing to collect evidence, examine surveillance footage, and follow up on any leads that may bring them closer to solving the case.
The Cincinnati Police Department has promised to provide further updates as new information becomes available. Residents are being asked to stay vigilant and report any suspicious activity that could aid in the investigation.
Conclusion
The death of John Joshua Isome in Over-the-Rhine has shocked the local community and left many searching for answers. The investigation is in its early stages, and law enforcement is urging the public to assist in any way they can to help identify the person responsible for this tragic shooting.
As the investigation continues, authorities remain committed to bringing justice to Isome’s family and ensuring that those responsible for this violent crime are held accountable.